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Protein chemistry

Program: 
Chemistry
ECTS: 
4
Lecturer: 
Prof. Zbigniew Szewczuk
Type: 
Optional
Level: 
Medium
Lecture
Number of hours: 
1h X 15 weeks = 15 hours (1 semester)
Laboratory
Number of hours: 
1h X 15 weeks = 15 hours (1 semester)
Objective: 

Knowledge of peptide and protein chemistry, with emphasis on peptide synthesis and chemical modification of proteins.
Acquired Knowledge
Student:
• Knows and understands chemical properties od amino acids, peptides and proteins
• Understands basic methods (isolation, synthesis purification and analysis) used in peptide and protein chemistry
Acquired Skills
Student:
• Is able to propose a method of synthesis and purification of peptides, based on their sequence
• Has basic laboratory skills including isolation, purification and characterization of peptides and proteins.
• Writes research reports
Social Competence
• a responsibility for accurate experimental work and critical data interpretation
• respecting laboratory safety rules

Assessment: 

Lecture: an oral exam.
Laboratory: The day-by-day assessment conducted by the instructor during the laboratory work and evaluation of written report on performed experiments.

Prerequisites: 

The course on organic chemistry should be already credited

Contents: 

Lecture (one semester 15h in total):

1. Chemical properties of amino acids.

2. Protein structures

3. Synthesis of peptides and peptidomimetics.

4. Protein purification and characterization.

5. Chemical and enzymatic modifications of proteins.

Laboratory (one semester, 15h,):

Implementation of methods presented in the lecture. For protein isolation and analysis