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  • Please note that in July the office hours will be like following:

    Monday, Tuesday, Thursday, Friday 9am-1pm

    Wednesday closed

    Sorry for all inconveniences.

  • Due to the renovation of the room 109, the International Office - (only the staff from the room 109) will be relocated to the room 320 (3rd floor, Institute of Geography)

    The office (room 109) will be closed during its removal on the 5 - 6th July. In urgant cases during those two days please visit our colleagues in the room 36 (ground floor).

    We apologise for any inconvenience.

Bioorganic chemistry with elements of molecular biology

Program: 
Chemistry
ECTS: 
4
Lecturer: 
dr hab. Piotr Stefanowicz
Type: 
Optional
Level: 
Medium
Lecture
Number of hours: 
1h X 15 weeks = 15 hours (1 semester)
Laboratory
Number of hours: 
1h X 15 weeks = 15 hours (1 semester)
Objective: 

Knowledge of foundations and contemporary problems of bioorganic chemistry
Acquired Knowledge
Student:
• Knows and understands stereochemistry of molecules of biological origin (sugars, nucleotides, lipids, amino acids, natural products)
• Understands the correlations between structures of chemical compounds and their biological activity
Acquired Skills:
Student:
• Is able to classify biomolecules and describe their sterochemical properties
• Has basic laboratory skills including isolation and characterization compounds from biological sources.
• Writes research reports
Personal and Social Competence
• respecting laboratory safety rules

Assessment: 

Lecture: an oral exam.
Laboratory: The day-by-day assessment conducted by the instructor during the laboratory work and evaluation of written report on performed experiments.

Contents: 

Lecture (one semester 15 h in total):

I. Molecules of Life

1. Chemical bonds and shape of organic molecules

2. Nucleotides and nucleic acids

3. Amino acids, peptides and proteins

4. Carbohydrates and lipids

5. „Natural Products” – secondary metabolites

II. Biological Activity1. Quantitative aspects of biological activity2. Examples of molecular targets: receptors, ion channels and their ligands3. Molecules interacting with nucleic acids4. Enzyme inhibitors and molecules interacting with proteins involved in cellular adhesion 5. Designing of biologically active compounds

Laboratory (one semester, 15 h,):

Isolation of natural products from biological sources.

1. Chemical and spectroscopic characterization of organic compounds.

2. Chromatographic methods: TLC, gel filtration, HPLC.

3. Peptide chemistry: synthesis and sequence analysis.